Dupuytren’s contracture, also known as Dupuytren’s disease, or Dupuytren’s syndrome is a medical condition that affects the hand’s connective tissue, specifically the palmar fascia, which is a layer of tissue located beneath the skin of the palm. This condition is characterized by the gradual thickening and tightening of the palmar fascia, leading to finger contractures and reduced hand function. It most commonly affects the ring finger and pinky finger, although it can affect other fingers as well.
The exact cause of Dupuytren’s contracture is not fully understood, but it is believed to be influenced by both genetic and environmental factors. It tends to be more common in people of Northern European descent and is often associated with certain risk factors, such as age (typically in middle-aged and older individuals), being male, smoking, and a family history of the condition.
Symptoms of Dupuytren’s contracture may start with the formation of small lumps or nodules in the palm, which can be tender but are not usually painful. Over time, as the condition progresses, the nodules can develop into thick cords of tissue that restrict the movement of the affected fingers. In severe cases, this can lead to significant hand deformity and functional limitations.
Treatment options for Dupuytren’s contracture include:
1. Observation: In some cases, the condition progresses slowly and may not require immediate treatment. Regular monitoring may be recommended.
2. Non-surgical treatments: These may include physical therapy, splinting, and steroid injections to manage symptoms and improve hand function.
4. Surgical intervention: In more advanced cases or when non-surgical treatments are ineffective, surgical procedures like fasciotomy or fasciectomy may be necessary to remove the affected tissue and restore hand function.
5. Minimally invasive procedures: Procedures such as needle aponeurotomy (NA) or collagenase injections can be used to break up the contracted tissue and improve finger mobility.
Xiaflex is a brand name for collagenase injections. It is used in the treatment of Dupuytren’s contracture.
Xiaflex is an enzyme that is injected directly into the Dupuytren’s cord, which is the thickened tissue causing the finger contracture. The enzyme works by breaking down collagen, a protein that contributes to the tightness and contraction of the tissue. By enzymatically weakening and dissolving the collagen, Xiaflex can help to straighten the affected finger(s) and improve hand function.
Treatment with Xiaflex involves an injection into the collagen “cord” that is causing the contracture by a doctor who is trained in the use of Xiaflex. 1-3 days after the injection, your physician will perform a finger manipulation to straighten the finger further.
It’s important to note that Xiaflex is not suitable for all cases of Dupuytren’s contracture, and the decision to use this medication should be made in consultation with a healthcare provider. The choice of treatment, whether Xiaflex or another approach like surgery, depends on the severity of the condition, the patient’s overall health, and individual factors. Potential side effects and risks associated with Xiaflex should also be discussed with a healthcare professional.
The choice of treatment depends on the severity of the condition, the patient’s overall health, and their individual preferences. Dupuytren’s contracture can be a chronic condition, and while treatment can help manage its symptoms, it may not always prevent its progression or recurrence. Early diagnosis and intervention are essential for better outcomes. If you suspect you have Dupuytren’s contracture or are experiencing hand-related symptoms,
Dupuytren’s contracture, also known as Dupuytren’s disease or Dupuytren’s syndrome, is a medical condition that affects the hand’s connective tissue, specifically the palmar fascia, which is a layer of tissue located beneath the skin of the palm. This condition is characterized by the gradual thickening and tightening of the palmar fascia, leading to finger contractures and reduced hand function. It most commonly affects the ring finger and pinky finger, although it can affect other fingers as well.
The exact cause of Dupuytren’s contracture is not fully understood, but it is believed to be influenced by both genetic and environmental factors. It tends to be more common in people of Northern European descent and is often associated with certain risk factors, such as age (typically in middle-aged and older individuals), being male, smoking, and a family history of the condition.
Symptoms of Dupuytren’s contracture may start with the formation of small lumps or nodules in the palm, which can be tender but are not usually painful. Over time, as the condition progresses, the nodules can develop into thick cords of tissue that restrict the movement of the affected fingers. In severe cases, this can lead to significant hand deformity and functional limitations.
The choice of treatment depends on the severity of the condition, the patient’s overall health, and their individual preferences. Dupuytren’s contracture can be a chronic condition, and while treatment can help manage its symptoms, it may not always prevent its progression or recurrence. Early diagnosis and intervention are essential for better outcomes. If you suspect you have Dupuytren’s contracture or are experiencing hand-related symptoms, Iowa Ortho’s hand doctors are professionals who are able to consult with you for an accurate diagnosis and appropriate management. Request an appointment here or call 515-247-8400 today