MACI Implants

At Iowa Ortho, we offer MACI (Matrix-Induced Autologous Chondrocyte Implantation)—a cutting-edge, FDA-approved treatment designed to repair cartilage damage in the knee using your body’s own cells. This regenerative procedure is ideal for active individuals experiencing knee pain, swelling, or limited mobility due to cartilage defects.

Understanding MACI
Cartilage is the smooth, rubbery tissue that cushions joints and enables easy movement. When damaged, it can lead to pain and decreased function. MACI addresses this by utilizing your own cartilage cells (chondrocytes) to regenerate healthy tissue.

The MACI Procedure at Iowa Ortho
The MACI treatment involves a three-step process:

Biopsy: A small sample of healthy cartilage is arthroscopically collected from a non-weight-bearing area of your knee. This sample is sent to a specialized facility in Massachusetts, where chondrocytes are extracted, expanded, and seeded onto a porcine collagen membrane. This process can take up to six weeks, during which multiple quality control tests ensure the implant’s safety and efficacy.
Implantation: Once ready, the MACI implant is delivered to Iowa Ortho. During a minimally invasive procedure, our surgeons precisely size and place the implant into the cartilage defect. The implant is secured using a sealant, eliminating the need for stitches.
Rehabilitation: Rehabilitation begins shortly after surgery, as recommended by your physician. Patients typically return to normal activities within 9 to 12 weeks, depending on individual progress.

Benefits of MACI

Customized Treatment: Utilizes your own cells for personalized healing.
Minimally Invasive: Reduces recovery time and surgical risks.
Effective Results: Studies have shown significant improvements in pain reduction and knee function.
Durable Implants: MACI implants are flexible, dual-sided, and durable, designed to integrate seamlessly with your knee tissue.

Is MACI Right for You?
MACI is suitable for patients who:

Are between 18 and 55 years old.
Have specific cartilage defects in the knee (e.g., Medial Femoral Condyle, Lateral Femoral Condyle, Trochlea).
Lead an active lifestyle and wish to return to high-impact activities.
Have not found relief through conservative treatments.

Our orthopedic specialists at Iowa Ortho will conduct a thorough evaluation to determine if MACI is the appropriate treatment for your condition.